What Are the Best Mushrooms for Chronic Pain? - Xotic Mushrooms

What Are the Best Mushrooms for Chronic Pain?

Chronic pain can be debilitating, affecting the quality of life for those who experience it. 

While there are various treatment options available, some individuals seek natural alternatives to manage their chronic pain. One such option gaining popularity is the use of mushrooms. 

In this article, we will explore the best mushrooms for chronic pain relief, their potential benefits, and how to incorporate them into your pain management routine.

What Are the Best Mushrooms for Chronic Pain?

Lion's Mane has the potential to support nerve health and reduce inflammation. Cordyceps mushrooms have also been studied for their anti-inflammatory properties, which may help alleviate chronic pain symptoms. Reishi mushrooms are often lauded for their immune-modulating effects and potential pain-relieving properties. Chaga mushrooms, rich in antioxidants, may contribute to reducing inflammation and promoting overall well-being. Additionally, King Trumpet mushrooms are recognized for their potential anti-inflammatory benefits. 

NOTE: While these mushrooms show promise, consulting with a healthcare professional is essential for personalized advice and to determine the most suitable approach for managing chronic pain.

Best Mushrooms for Chronic Pain

When it comes to chronic pain management, certain mushrooms have shown promise in providing relief. While individual responses can vary, several mushrooms are commonly recognized for their potential benefits

Mushrooms can help decrease inflammation, immune support, balancing blood sugar levels, helping with nerve growth factor, decreasing pain, and increasing energy.

Here are the top 5 mushrooms that can help handle chronic pain.

1. Lion’s Mane Mushrooms

Lion's mane mushrooms, scientifically known as Hericium erinaceus, have shown promising results in alleviating chronic pain. 

These mushrooms not only promote nerve growth and recovery but also appear to ease nerve pain. These mushrooms can stimulate the production of nerve growth factor (NGF) proteins, aiding in the regeneration of damaged nerves.

Other Benefits of Lion’s Mane Mushrooms

Aside from pain relief, lion's mane mushrooms offer additional benefits such as memory enhancement and cognitive function improvement

They have been studied for their potential in treating conditions like depression and Alzheimer's disease.

How to Use Lion's Mane for Pain Relief

Lion's mane mushrooms can be consumed in various forms, including fresh, dried, or as a dietary supplement. 

Incorporating lion's mane mushrooms into your diet can be as simple as adding them to stir-fries, soups, or stews. 

Alternatively, you can opt for lion's mane supplements available in capsule or powder form.

2. Cordyceps Mushrooms

Cordyceps mushrooms (Cordyceps militaris) have been traditionally used in herbal medicine for their adaptogenic properties. 

While there is limited direct research on their effects on chronic pain, cordyceps mushrooms show promise in reducing inflammation, which is often associated with pain.

They can help treat rheumatoid arthritis, systemic lupus, and Crohn's disease.

Other Benefits of Cordyceps Mushrooms

They can help increase energy levels, improve athletic performance, and enhance respiratory function. They are also known for their antioxidant properties.

How to Use Cordyceps for Pain Relief

Cordyceps mushrooms can be consumed in various forms, such as dried mushrooms or cordyceps extracts. They can be brewed into tea, added to smoothies, or incorporated into cooking recipes.

3. Reishi Mushrooms

Reishi mushrooms (Ganoderma lucidum) are highly regarded for their overall health benefits. They have been studied for their anti-inflammatory properties and have shown potential in providing pain relief, particularly for conditions like Herpes zoster.

Other Benefits of Reishi Mushrooms

Reishi mushrooms have been associated with immune system support, improved sleep quality, and stress reduction which can reduce pain indirectly.

They are rich in antioxidants and may aid in the management of allergies and asthma.

They have also shown great promise in reducing inflammation and balancing the gut microbiome.

How to Use Reishi Mushrooms for Pain Relief

Reishi mushrooms are available in various forms, including dried slices, powder, or as a supplement. They can be brewed into tea or added to hot beverages like coffee, tincture, or cocoa.

4. Chaga Mushrooms

Chaga mushrooms (Inonotus obliquus) are known for their antioxidant and anti-inflammatory properties, making them potentially beneficial for chronic pain relief. 

Studies suggest that chaga mushrooms can help reduce inflammation and alleviate pain by blocking proteins associated with pain and inflammation.

Other Benefits of Chaga Mushrooms

Chaga mushrooms are also believed to support immune system function, promote skin health, and offer anti-aging properties

They are often used as a natural remedy for boosting overall well-being.

How to Use Chaga Mushrooms for Pain Relief

Chaga mushrooms can be consumed as a tea by steeping dried chaga chunks or powder in hot water. Alternatively, chaga extract powders and supplements are available for convenient consumption.

5. King Trumpet

While not as extensively studied as the previous mushrooms mentioned, king trumpet mushrooms (Pleurotus eryngii) have shown potential in reducing inflammation and providing pain relief. They are rich in antioxidants and have a meaty texture, making them a versatile ingredient in culinary applications.

Other Benefits of King Trumpet Mushrooms

King trumpet mushrooms offer nutritional benefits, including vitamins, minerals, and fiber. They are also low in calories, making them a suitable addition to a balanced diet.

How to Use King Trumpet Mushrooms for Pain Relief

King trumpet mushrooms can be cooked in various ways, such as grilling, roasting, sautéing, or incorporating them into dishes like soups, stir-fries, or pasta.

Best Ways to Take Medicinal Mushrooms for Chronic Pain

Incorporating medicinal mushrooms into your routine for chronic pain relief can be done in different ways. 

These include consuming mushrooms in their natural form, incorporating them into meals, preparing mushroom teas, or using mushroom extracts and supplements. 

It is advisable to consult with a healthcare professional or a knowledgeable practitioner before starting any new supplements or making significant changes to your diet.


What is the best mushroom for osteoarthritis?

While there is no specific mushroom that has been identified as the best for osteoarthritis, certain mushrooms like Hericium erinaceus have shown potential in reducing inflammation, which may help alleviate symptoms associated with osteoarthritis.

How do people cope with constant pain?

Coping with constant pain can be challenging, but there are several strategies that individuals can try. These may include seeking medical advice, exploring pain management techniques such as mindfulness and relaxation exercises, maintaining a healthy lifestyle, engaging in physical therapy, and considering complementary approaches like incorporating mushrooms for natural pain relief.

What is the best mushroom for depression?

While mushrooms are not a replacement for professional treatment of depression, some mushrooms like lion's mane have been studied for their potential in supporting cognitive function and improving mood

Which mushroom is best for joint health?

Mushrooms rich in anti-inflammatory properties, such as reishi and cordyceps, may potentially benefit joint health. These mushrooms may help reduce inflammation, which can contribute to joint pain and stiffness.

What is the best mushroom for arthritis and inflammation?

Mushrooms with anti-inflammatory properties, such as reishi and chaga, have shown potential for arthritis and inflammation relief. They may help reduce inflammation and alleviate symptoms associated with arthritis. However, individual responses can vary, and it is advisable to consult with a healthcare professional for personalized advice.

What is the best mushroom for autoimmune disease?

While mushrooms may offer potential benefits for immune system support, there is no specific mushroom identified as the best for autoimmune diseases. Medicinal mushrooms like reishi and cordyceps are often studied for their immune-modulating properties, but it is essential to consult with a healthcare professional to determine appropriate treatment options for autoimmune diseases.

What is the best mushroom for gut health?

Mushrooms with prebiotic properties, such as lion's mane and king trumpet, may contribute to gut health by supporting the growth of beneficial gut bacteria. These mushrooms can potentially help improve digestion and overall gut function. However, a balanced diet rich in fiber and diverse plant-based foods is essential for optimal gut health.

Should I take psychedelic mushrooms for pain relief?

Psychedelic mushrooms, such as psilocybin-containing mushrooms, are a different category from medicinal mushrooms discussed in this article. Psychedelic mushrooms are not recommended or approved for pain relief purposes. It is important to adhere to legal and medical guidelines regarding the use of any substances and consult with a healthcare professional for appropriate pain management options.


While more research is needed to fully understand the potential of mushrooms in chronic pain relief, several varieties have shown promising results. 

Lion's mane, cordyceps, reishi, chaga, and king trumpet mushrooms offer various benefits and can be incorporated into your pain management routine. 

However, it is essential to consult with a healthcare professional before adding mushrooms or any new supplements to your regimen. 

Embracing a holistic approach to pain management may provide natural relief and improve overall well-being.

Back to blog